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Module 5: Comorbidity-Specific Treatment

Preferred and avoided antihypertensive agents based on comorbid conditions including CKD, heart failure, CAD, diabetes, and stroke.

1.BP Classification2.Treatment Initiation3.Medication Selection4.BP Goals5.Comorbidities6.Resistant HTN7.Special Populations8.Lifestyle9.Monitoring

Comorbid Conditions

Lab Values & Measurements

mL/min/1.73m²

eGFR <60 = CKD

mg/g

≥30 mg/g = microalbuminuria

%

≤40% = HFrEF; >40% = HFpEF

kg/m²

≥30 = obesity

Select comorbid conditions above to see drug preferences and agents to avoid.

Source: 2025 AHA/ACC HTN Guideline, Section 5.3.

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