Module 4: PE Category Assignment

Assign the 2026 AHA/ACC Clinical Category (A through E2) with R modifier based on hemodynamic status, biomarkers, and RV function.

Category Not Yet Assigned

Complete to assign category:

  • !Symptomatic status (symptomatic vs. incidental)
  • !Hemodynamic status (hemodynamic stability)

Key Category Determinants

Presentation

Hemodynamic Status

Biomarkers & RV (for Category C sub-classification)

R Modifier (respiratory compromise)

Category Spectrum (2026 AHA/ACC Guideline, Figure 2)

A
Low
B1
Low
B2
Low
C1
Intermediate-Low
C2
Intermediate-Low
C3
Intermediate-High
D1
High
D2
High
E1
Massive
E2
Massive

IMPORTANT: This software is clinical decision support (CDS) intended for use by licensed healthcare professionals under Section 520(o)(1)(E) of the Federal Food, Drug, and Cosmetic Act. It is not intended as a medical device. All recommendations are derived from the 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism (Circulation 2026;153:e977-e1051) and must be independently verified by the treating clinician before any clinical action. AI-generated content (including extracted data and clinical notes) is produced by large language models and may contain errors, omissions, or hallucinations — clinician review is mandatory. Patient data entered into the calculator is processed entirely in the browser; AI features process data server-side under a signed HIPAA Business Associate Agreement with no data retention. AI-HEART Lab, its affiliates, and contributors assume no liability for clinical decisions made using this tool. By using this tool, you acknowledge these limitations and accept full responsibility for clinical decisions.