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Module 1: Pre-Test Probability

Calculate Wells PE score, Revised Geneva score, PERC rule, and YEARS algorithm to determine pre-test probability of pulmonary embolism.

Pre-Test Prob.D-DimerSeverity (PESI)Category (A–E)Hestia CriteriaAnticoagulationDurationAdvanced RxSpecial Populations

Wells PE Score

0
points

Source: 2026 AHA/ACC PE Guideline, Table 3

2-Level (Preferred)
PE Unlikely (score ≤4)
3-Level
Low Probability (score <2)

Revised Geneva Score

0
original · 0 simplified

Source: 2026 AHA/ACC PE Guideline, Table 3 — Objective tool (no clinical gestalt required)

Original Revised Geneva
Low Probability (score 0–3)
Simplified Geneva
Low Probability (score 0–1)

PERC Rule

Class I / Level B-NR

All 8 criteria must be present (negative) to apply PERC rule-out. Requires Wells <2 (pre-test probability <15%).

PE Not Excluded
  • •Age ≥50 years (PERC requires <50)
  • •Heart rate ≥100 bpm (PERC requires <100)
  • •SpO2 <95% (PERC requires ≥95%)
  • •Hemoptysis present (PERC requires absent)
  • •Exogenous estrogen use (PERC requires absent)
  • •Prior DVT or PE (PERC requires absent)
  • •Unilateral leg swelling (PERC requires absent)
  • •Surgery/trauma requiring hospitalization within 4 weeks (PERC requires absent)

YEARS Algorithm

Class IIa / Level B-R

Source: 2026 AHA/ACC PE Guideline, Section 3.1.1, Recommendation 3. D-dimer threshold varies by item count.

0 YEARS item(s) present
D-dimer threshold: 1000 μg/L FEU

0 items → elevated threshold of 1000 μg/L (highly specific)

IMPORTANT: This software is clinical decision support (CDS) intended for use by licensed healthcare professionals under Section 520(o)(1)(E) of the Federal Food, Drug, and Cosmetic Act. It is not intended as a medical device. All recommendations are derived from the 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism (Circulation 2026;153:e977-e1051) and must be independently verified by the treating clinician before any clinical action. AI-generated content (including extracted data and clinical notes) is produced by large language models and may contain errors, omissions, or hallucinations — clinician review is mandatory. Patient data entered into the calculator is processed entirely in the browser; AI features process data server-side under a signed HIPAA Business Associate Agreement with no data retention. AI-HEART Lab, its affiliates, and contributors assume no liability for clinical decisions made using this tool. By using this tool, you acknowledge these limitations and accept full responsibility for clinical decisions.